top of page

Benhamou Research Group

Chemical Biology & Drug Design 

About the lab

Our research laboratory focuses on the emerging role of RNA as a therapeutic target, positioned at the intersection of chemical biology, medicinal chemistry, and molecular/cellular biology. We leverage organic chemistry to address fundamental questions in RNA biology, with the aim of synthesizing and evaluating small molecules that bind to and modulate the function of specific RNA motifs in disease models. These small molecules serve as probes to explore RNA complexes or as potential drugs to alleviate disease-related phenotypes. Our work spans a broad range of pathologies, from genetic diseases like cancer to obesity, depression orinfectious diseases.

About the lab-home

News & Events

22.11.2024: New research article published in Macromolecular Bioscience - Congrats to Aseel and the team! - "PROTAC and Molecular Glue Degraders of the Oncogenic RNA Binding Protein Lin28"

20.11.2024Research Webinar | Benhamou Lab - webinar showcasing our recent breakthroughs in developing small molecule therapies targeting RNA

01.10.2024: We welcome five new students to our lab: three new master's students—Liann, Leora, and Binyamin—and two undergraduate students, Hadas and Leen.

18.07.2024: Congrats to Aseel and Elias for presenting their work as posters at the 2024 MCS-ICS meeting! Special applause to Aseel for winning the Best Poster Prize! 

 

18.07.2024: Congratulations to Raphael for receiving the 2024 NCK medicinal chemistry prize for outstanding young chemist, Medicinal Chemistry Section of the Israel Chemical Society (MCS-ICS).

Open Positions 

Come join a new and exciting lab at the Hebrew University of Jerusalem (HUJI).

We are looking for talented, highly motivated M.Sc, Ph.D., and postdocs to join our team.

לוגו האוניברסיטה העברית בירושלים
לוגו הפקולטה לרפואה
לוגו המכון למדעי התרופה
Logo color copy.png
bottom of page