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News & Events
New Review! - Small Molecules Targeting MicroRNAs
In this review, we explore advancements in drug discovery, focusing on the potential to selectively target specific disease-associated miRs.
Congratulation to Kisanet!
Congratulation to Kisanet!
We welcome Dipak and Omri!
Dipak is joining the lab as a Postdoc and Omri as a new M.Sc. student. Welcome and good luck!
New published article! Targeted Degradation of Structured RNAs via Ribonuclease-Targeting Chimeras (RiboTacs)
Check out our review and thoughts on the evolution of the RIBOTAC technology for degrading structured RNAs associated with diseases.
Congrats to Salma Haj yahya and Arijit Nandi!
Congrats to Salma Haj yahya and Arijit Nandi!
Congratulations to our Master's students, Salma Haj Yahya and Elias Khaskia.
Congratulations to two of our Master's students, Salma Haj Yahya and Elias Khaskia, for delivering amazing master seminar talks today!
You have made us proud!
You have made us proud!
New Research Article Published in Nature!
Target occupancy is often insufficient to elicit biological activity, particularly for RNA, compounded by the longstanding challenges surrounding the molecular recognition of RNA structures by small molecules. Here we developed a strategy that converts biologically inactive RNA-binding small molecules into potent and specific effectors of function, achieved by affixing an RNA molecular recognition element to a second compound that binds to and activates a ribonuclease to cleave the target.
"Programming inactive RNA-binding small molecules into bioactive degraders". Nature 2023
"Programming inactive RNA-binding small molecules into bioactive degraders". Nature 2023
We welcome Arijit, a new PhD student to the Benhamou lab!
Arijit joined us from India to pursue his PhD with us! Welcome and good luck Arijit!
New Grant! Science Forefront
The minister of science granted our research in collaboration with Dr. Gali Umshweif. We seek to develop novel molecules to fight depression.
We finally moved to our new lab space!
We have brand-new equipment and a splendid view over Jerusalem Mountain. If you are around come visit us!
New M.Sc. Students
We welcome Elias, Kisanet and Aseel! They are joining the lab as new M.Sc. students!
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